5MWO
Structure of Mycobacterium Tuberculosis Transcriptional Regulatory Repressor Protein (EthR) in complex with fragment 7E8.
Summary for 5MWO
Entry DOI | 10.2210/pdb5mwo/pdb |
Descriptor | HTH-type transcriptional regulator EthR, (5-methyl-1-benzothiophen-2-yl)methanol, 1,2-ETHANEDIOL, ... (4 entities in total) |
Functional Keywords | ethr, repressor, tetr, mycobacterium tuberculosis, transcription |
Biological source | Mycobacterium tuberculosis H37Rv |
Total number of polymer chains | 1 |
Total formula weight | 25677.82 |
Authors | Mendes, V.,Chan, D.S.-H.,Thomas, S.E.,McConnell, B.,Matak-Vinkovic, D.,Coyne, A.G.,Abell, C.,Blundell, T.L. (deposition date: 2017-01-18, release date: 2017-05-31, Last modification date: 2024-01-17) |
Primary citation | Chan, D.S.,Mendes, V.,Thomas, S.E.,McConnell, B.N.,Matak-Vinkovic, D.,Coyne, A.G.,Blundell, T.L.,Abell, C. Fragment Screening against the EthR-DNA Interaction by Native Mass Spectrometry. Angew. Chem. Int. Ed. Engl., 56:7488-7491, 2017 Cited by PubMed: 28513917DOI: 10.1002/anie.201702888 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.962 Å) |
Structure validation
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