5MWO

Structure of Mycobacterium Tuberculosis Transcriptional Regulatory Repressor Protein (EthR) in complex with fragment 7E8.

5MWO の概要

• エントリーDOI: 10.2210/pdb5mwo/pdb
• 分子名称: HTH-type transcriptional regulator EthR, (5-methyl-1-benzothiophen-2-yl)methanol, 1,2-ETHANEDIOL, ... (4 entities in total)
• 機能のキーワード: ethr, repressor, tetr, mycobacterium tuberculosis, transcription
• 由来する生物種: Mycobacterium tuberculosis H37Rv
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 25677.82

構造登録者

Mendes, V.,Chan, D.S.-H.,Thomas, S.E.,McConnell, B.,Matak-Vinkovic, D.,Coyne, A.G.,Abell, C.,Blundell, T.L. (登録日: 2017-01-18, 公開日: 2017-05-31, 最終更新日: 2024-01-17)

• 主引用文献: Chan, D.S.,Mendes, V.,Thomas, S.E.,McConnell, B.N.,Matak-Vinkovic, D.,Coyne, A.G.,Blundell, T.L.,Abell, C.; Fragment Screening against the EthR-DNA Interaction by Native Mass Spectrometry.; Angew. Chem. Int. Ed. Engl., 56:7488-7491, 2017; PubMed: 28513917; DOI: 10.1002/anie.201702888

実験手法

X-RAY DIFFRACTION (1.962 Å)