5MV4
ACC1 Fab fragment in complex with citrullinated CII616-639 epitope of collagen type II (ptm23)
5MV4 の概要
エントリーDOI | 10.2210/pdb5mv4/pdb |
分子名称 | ACC1 antibody Fab fragment, heavy chain, ACC1 antibody Fab fragment, light chain, synthetic peptide containing the citrullinated collagen type II epitope CII616-639,Collagen alpha-1(II) chain,synthetic peptide containing the citrullinated collagen type II epitope CII616-639, ... (5 entities in total) |
機能のキーワード | anti-citrullinated protein antibody (acpa) fab fragment collagen type ii citrullinated c1 epitope, immune system |
由来する生物種 | Mus musculus (Mouse) 詳細 |
タンパク質・核酸の鎖数 | 24 |
化学式量合計 | 410469.96 |
構造登録者 | |
主引用文献 | Ge, C.,Tong, D.,Liang, B.,Lonnblom, E.,Schneider, N.,Hagert, C.,Viljanen, J.,Ayoglu, B.,Stawikowska, R.,Nilsson, P.,Fields, G.B.,Skogh, T.,Kastbom, A.,Kihlberg, J.,Burkhardt, H.,Dobritzsch, D.,Holmdahl, R. Anti-citrullinated protein antibodies cause arthritis by cross-reactivity to joint cartilage. JCI Insight, 2:-, 2017 Cited by PubMed: 28679953DOI: 10.1172/jci.insight.93688 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (2.9 Å) |
構造検証レポート
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