5MUF
Crystal structure of human phosphoglycerate mutase family member 5 (PGAM5) in its enzymatically active dodecameric form induced by the presence of the N-terminal WDPNWD motif
5MUF の概要
エントリーDOI | 10.2210/pdb5muf/pdb |
関連するPDBエントリー | 3MXO 3O0T |
分子名称 | Serine/threonine-protein phosphatase PGAM5, mitochondrial, PHOSPHATE ION (3 entities in total) |
機能のキーワード | phosphoglycerate mutase family member 5, pgam5, serine/threonine phosphatase, mitochondrial protein, hydrolase, wdpnwd motif, wdxnwd motif, dimer, dodecamer, structural genomics, structural genomics consortium, sgc |
由来する生物種 | Homo sapiens (Human) |
細胞内の位置 | Mitochondrion outer membrane ; Single-pass membrane protein : Q96HS1 |
タンパク質・核酸の鎖数 | 3 |
化学式量合計 | 81701.60 |
構造登録者 | Chaikuad, A.,Alfano, I.,Picaud, S.,Filippakopoulos, P.,von Delft, F.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.M.,Knapp, S.,Structural Genomics Consortium (SGC) (登録日: 2017-01-13, 公開日: 2017-07-12, 最終更新日: 2024-01-17) |
主引用文献 | Chaikuad, A.,Filippakopoulos, P.,Marcsisin, S.R.,Picaud, S.,Schroder, M.,Sekine, S.,Ichijo, H.,Engen, J.R.,Takeda, K.,Knapp, S. Structures of PGAM5 Provide Insight into Active Site Plasticity and Multimeric Assembly. Structure, 25:1089-1099.e3, 2017 Cited by PubMed: 28648608DOI: 10.1016/j.str.2017.05.020 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (3.1 Å) |
構造検証レポート
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