5MUC

Crystal structure of the FimH lectin domain in complex with 1,5-Anhydromannitol

5MUC の概要

• エントリーDOI: 10.2210/pdb5muc/pdb
• 分子名称: Protein FimH, 1-deoxy-alpha-D-mannopyranose (3 entities in total)
• 機能のキーワード: fimh, uti, lectin, carbohydrate, upec, bladder infection, sugar binding protein
• 由来する生物種: Escherichia coli (strain K12)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 34161.97

構造登録者

Jakob, R.P.,Rabbani, S.,Ernst, B.,Maier, T. (登録日: 2017-01-13, 公開日: 2018-02-14, 最終更新日: 2024-01-17)

• 主引用文献: Zihlmann, P.,Silbermann, M.,Sharpe, T.,Jiang, X.,Muhlethaler, T.,Jakob, R.P.,Rabbani, S.,Sager, C.P.,Frei, P.,Pang, L.,Maier, T.,Ernst, B.; KinITC-One Method Supports both Thermodynamic and Kinetic SARs as Exemplified on FimH Antagonists.; Chemistry, 24:13049-13057, 2018; PubMed: 29939458; DOI: 10.1002/chem.201802599

実験手法

X-RAY DIFFRACTION (2.6 Å)