5MTV
Active structure of EHD4 complexed with ATP-gamma-S
Summary for 5MTV
Entry DOI | 10.2210/pdb5mtv/pdb |
Descriptor | EH domain-containing protein 4, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, MAGNESIUM ION, ... (4 entities in total) |
Functional Keywords | dynamin-like, membrane protein, auto-inhibition, activation, endocytosis |
Biological source | Mus musculus (House Mouse) |
Cellular location | Early endosome membrane ; Peripheral membrane protein ; Cytoplasmic side : Q9EQP2 |
Total number of polymer chains | 1 |
Total formula weight | 60035.63 |
Authors | Melo, A.A.,Daumke, O. (deposition date: 2017-01-10, release date: 2017-03-08, Last modification date: 2024-01-17) |
Primary citation | Melo, A.A.,Hegde, B.G.,Shah, C.,Larsson, E.,Isas, J.M.,Kunz, S.,Lundmark, R.,Langen, R.,Daumke, O. Structural insights into the activation mechanism of dynamin-like EHD ATPases. Proc. Natl. Acad. Sci. U.S.A., 114:5629-5634, 2017 Cited by PubMed: 28228524DOI: 10.1073/pnas.1614075114 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.79 Å) |
Structure validation
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