5MTO

N-terminal domain of the human tumor suppressor ING5 C19S mutant

Summary for 5MTO

• Entry DOI: 10.2210/pdb5mto/pdb
• Related: 5MTO
• Descriptor: Inhibitor of growth protein 5, SODIUM ION, SULFATE ION, ... (4 entities in total)
• Functional Keywords: ing5, tumor suppressor, signaling protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 25211.45

Authors

Ormaza, G.,Buitrago, J.A.R.,Roversi, P.,Rojas, A.L.,Blanco, F.J. (deposition date: 2017-01-10, release date: 2018-02-28, Last modification date: 2024-01-17)

• Primary citation: Ormaza, G.,Rodriguez, J.A.,Ibanez de Opakua, A.,Merino, N.,Villate, M.,Gorrono, I.,Rabano, M.,Palmero, I.,Vilaseca, M.,Kypta, R.,Vivanco, M.D.M.,Rojas, A.L.,Blanco, F.J.; The Tumor Suppressor ING5 Is a Dimeric, Bivalent Recognition Molecule of the Histone H3K4me3 Mark.; J.Mol.Biol., 431:2298-2319, 2019; PubMed: 31026448; DOI: 10.1016/j.jmb.2019.04.018

Experimental method

X-RAY DIFFRACTION (3.1 Å)