5MR5
Ligand-receptor complex.
Summary for 5MR5
| Entry DOI | 10.2210/pdb5mr5/pdb |
| Descriptor | Neurturin, GDNF family receptor alpha-2, SULFATE ION, ... (5 entities in total) |
| Functional Keywords | complex, receptor, signalling, ligand-receptor complex, signaling protein |
| Biological source | Homo sapiens (Human) More |
| Cellular location | Secreted: Q99748 Cell membrane ; Lipid-anchor, GPI-anchor : O00451 |
| Total number of polymer chains | 4 |
| Total formula weight | 73970.98 |
| Authors | Sandmark, J.,Oster, L.,Aagaard, A.,Roth, R.,Dahl, G. (deposition date: 2016-12-21, release date: 2018-01-17, Last modification date: 2024-01-17) |
| Primary citation | Sandmark, J.,Dahl, G.,Oster, L.,Xu, B.,Johansson, P.,Akerud, T.,Aagaard, A.,Davidsson, P.,Bigalke, J.M.,Winzell, M.S.,Rainey, G.J.,Roth, R.G. Structure and biophysical characterization of the human full-length neurturin-GFRa2 complex: A role for heparan sulfate in signaling. J. Biol. Chem., 293:5492-5508, 2018 Cited by PubMed: 29414779DOI: 10.1074/jbc.RA117.000820 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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