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5MQL

Crystal structure of dCK mutant C3S in complex with masitinib and UDP

Summary for 5MQL
Entry DOI10.2210/pdb5mql/pdb
DescriptorDeoxycytidine kinase, URIDINE-5'-DIPHOSPHATE, Masitinib, ... (6 entities in total)
Functional Keywordsdeoxycytidine kinase, dck, masitinib, transferase
Biological sourceHomo sapiens (Human)
Cellular locationNucleus : P27707
Total number of polymer chains4
Total formula weight138846.76
Authors
Primary citationHammam, K.,Saez-Ayala, M.,Rebuffet, E.,Gros, L.,Lopez, S.,Hajem, B.,Humbert, M.,Baudelet, E.,Audebert, S.,Betzi, S.,Lugari, A.,Combes, S.,Letard, S.,Casteran, N.,Mansfield, C.,Moussy, A.,De Sepulveda, P.,Morelli, X.,Dubreuil, P.
Dual protein kinase and nucleoside kinase modulators for rationally designed polypharmacology.
Nat Commun, 8:1420-1420, 2017
Cited by
PubMed: 29127277
DOI: 10.1038/s41467-017-01582-5
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.25 Å)
Structure validation

221051

건을2024-06-12부터공개중

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