5MQF
Cryo-EM structure of a human spliceosome activated for step 2 of splicing (C* complex)
Summary for 5MQF
Entry DOI | 10.2210/pdb5mqf/pdb |
EMDB information | 3545 |
Descriptor | Pre-mRNA-processing-splicing factor 8, Pre-mRNA-splicing factor SYF1, Pre-mRNA-splicing factor SYF2, ... (35 entities in total) |
Functional Keywords | spliceosome, pre-mrna splicing, macromolecular complex, splicing |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 46 |
Total formula weight | 2666327.59 |
Authors | Bertram, K.,Hartmuth, K.,Kastner, B. (deposition date: 2016-12-20, release date: 2017-03-22, Last modification date: 2018-11-21) |
Primary citation | Bertram, K.,Agafonov, D.E.,Liu, W.T.,Dybkov, O.,Will, C.L.,Hartmuth, K.,Urlaub, H.,Kastner, B.,Stark, H.,Lu Hrmann, R. Cryo-EM structure of a human spliceosome activated for step 2 of splicing. Nature, 542:318-323, 2017 Cited by PubMed: 28076346DOI: 10.1038/nature21079 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (5.9 Å) |
Structure validation
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