5MOZ

OXA-10 Avibactam complex with bound Iodide

Summary for 5MOZ

• Entry DOI: 10.2210/pdb5moz/pdb
• Descriptor: Beta-lactamase OXA-10, (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, GLYCEROL, ... (7 entities in total)
• Functional Keywords: antibiotic resisitance, hydrolase
• Biological source: Pseudomonas aeruginosa
• Total number of polymer chains: 2
• Total formula weight: 57586.69

Authors

Brem, J. (deposition date: 2016-12-15, release date: 2017-07-12, Last modification date: 2024-01-17)

• Primary citation: Lohans, C.T.,Wang, D.Y.,Jorgensen, C.,Cahill, S.T.,Clifton, I.J.,McDonough, M.A.,Oswin, H.P.,Spencer, J.,Domene, C.,Claridge, T.D.W.,Brem, J.,Schofield, C.J.; (13)C-Carbamylation as a mechanistic probe for the inhibition of class D beta-lactamases by avibactam and halide ions.; Org. Biomol. Chem., 15:6024-6032, 2017; PubMed: 28678295; DOI: 10.1039/c7ob01514c

Experimental method

X-RAY DIFFRACTION (1.34 Å)