5MNH
Cationic trypsin in complex with benzamidine (deuterated sample at 295 K)
Summary for 5MNH
Entry DOI | 10.2210/pdb5mnh/pdb |
Descriptor | Cationic trypsin, CALCIUM ION, SULFATE ION, ... (5 entities in total) |
Functional Keywords | hydrogen bonding, protonation, protein-ligand interaction, hydrolase |
Biological source | Bos taurus (cattle) |
Total number of polymer chains | 1 |
Total formula weight | 23676.64 |
Authors | Schiebel, J.,Heine, A.,Klebe, G. (deposition date: 2016-12-13, release date: 2018-01-17, Last modification date: 2024-01-17) |
Primary citation | Schiebel, J.,Gaspari, R.,Wulsdorf, T.,Ngo, K.,Sohn, C.,Schrader, T.E.,Cavalli, A.,Ostermann, A.,Heine, A.,Klebe, G. Intriguing role of water in protein-ligand binding studied by neutron crystallography on trypsin complexes. Nat Commun, 9:3559-3559, 2018 Cited by PubMed: 30177695DOI: 10.1038/s41467-018-05769-2 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (0.93 Å) |
Structure validation
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