5MMY

Crystal structure of OXA10 with HEPES

Summary for 5MMY

Entry DOI	10.2210/pdb5mmy/pdb
Descriptor	Beta-lactamase OXA-10, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DIMETHYL SULFOXIDE, ... (8 entities in total)
Functional Keywords	antibiotic resistance oxacillinase carbapenems, hydrolase
Biological source	Pseudomonas aeruginosa
Total number of polymer chains	2
Total formula weight	56125.22
Authors	Brem, J. (deposition date: 2016-12-12, release date: 2017-07-12, Last modification date: 2024-01-17)
Primary citation	Lohans, C.T.,Wang, D.Y.,Jorgensen, C.,Cahill, S.T.,Clifton, I.J.,McDonough, M.A.,Oswin, H.P.,Spencer, J.,Domene, C.,Claridge, T.D.W.,Brem, J.,Schofield, C.J. (13)C-Carbamylation as a mechanistic probe for the inhibition of class D beta-lactamases by avibactam and halide ions. Org. Biomol. Chem., 15:6024-6032, 2017 Cited by PubMed: 28678295 DOI: 10.1039/c7ob01514c PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.88 Å)

Structure validation