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5MKV

Crystal Structure of Human Dihydropyrimidinease-like 2 (DPYSL2A)/Collapsin Response Mediator Protein (CRMP2) residues 13-516

5MKV の概要
エントリーDOI10.2210/pdb5mkv/pdb
分子名称Dihydropyrimidinase-related protein 2, 1,2-ETHANEDIOL (3 entities in total)
機能のキーワードcrmp2, ovarian cancer, microtubule associated protein, hydrolase
由来する生物種Homo sapiens (Human)
タンパク質・核酸の鎖数4
化学式量合計221782.12
構造登録者
Sethi, R.,Zheng, Y.,Krojer, T.,Velupillai, S.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Ahmed, A.A.,von Delft, F. (登録日: 2016-12-05, 公開日: 2017-02-22, 最終更新日: 2024-01-17)
主引用文献Zheng, Y.,Sethi, R.,Mangala, L.S.,Taylor, C.,Goldsmith, J.,Wang, M.,Masuda, K.,Karaminejadranjbar, M.,Mannion, D.,Miranda, F.,Herrero-Gonzalez, S.,Hellner, K.,Chen, F.,Alsaadi, A.,Albukhari, A.,Fotso, D.C.,Yau, C.,Jiang, D.,Pradeep, S.,Rodriguez-Aguayo, C.,Lopez-Berestein, G.,Knapp, S.,Gray, N.S.,Campo, L.,Myers, K.A.,Dhar, S.,Ferguson, D.,Bast, R.C.,Sood, A.K.,von Delft, F.,Ahmed, A.A.
Tuning microtubule dynamics to enhance cancer therapy by modulating FER-mediated CRMP2 phosphorylation.
Nat Commun, 9:476-476, 2018
Cited by
PubMed: 29396402
DOI: 10.1038/s41467-017-02811-7
主引用文献が同じPDBエントリー
実験手法
X-RAY DIFFRACTION (1.8 Å)
構造検証レポート
Validation report summary of 5mkv
検証レポート(詳細版)ダウンロードをダウンロード

217705

件を2024-03-27に公開中

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