5MIH

Crystal structure of the lectin LecA from Pseudomonas aeruginosa in complex with a phenyl-epoxy-galactopyranoside

5MIH の概要

• エントリーDOI: 10.2210/pdb5mih/pdb
• 分子名称: PA-I galactophilic lectin, CALCIUM ION, phenyl 6,7-anhydro-D-glycero-beta-D-galacto-heptopyranoside, ... (5 entities in total)
• 機能のキーワード: lectin, galactose binding protein, covalent lectin inhibition, sugar binding protein
• 由来する生物種: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
• 細胞内の位置: Cytoplasm: Q05097
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 52522.16

構造登録者

Wagner, S.,Hauk, D.,Hofmann, M.,Joachim, I.,Sommer, R.,Muller, R.,Imberty, A.,Varrot, A.,Titz, A. (登録日: 2016-11-28, 公開日: 2017-10-11, 最終更新日: 2024-01-17)

• 主引用文献: Wagner, S.,Hauck, D.,Hoffmann, M.,Sommer, R.,Joachim, I.,Muller, R.,Imberty, A.,Varrot, A.,Titz, A.; Covalent Lectin Inhibition and Application in Bacterial Biofilm Imaging.; Angew. Chem. Int. Ed. Engl., 56:16559-16564, 2017; PubMed: 28960731; DOI: 10.1002/anie.201709368

実験手法

X-RAY DIFFRACTION (1.8 Å)