5MI7

BtGH84 mutant with covalent modification by MA4 in complex with PUGNAc

5MI7 の概要

• エントリーDOI: 10.2210/pdb5mi7/pdb
• 分子名称: O-GlcNAcase BT_4395, O-(2-ACETAMIDO-2-DEOXY D-GLUCOPYRANOSYLIDENE) AMINO-N-PHENYLCARBAMATE, ~{N}-(4-morpholin-4-ylthieno[2,3-d]pyrimidin-2-yl)propanamide, ... (5 entities in total)
• 機能のキーワード: hydrolase, activator
• 由来する生物種: Bacteroides thetaiotaomicron VPI-5482
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 84287.21

構造登録者

Darby, J.F.,Davies, G.J.,Hubbard, R.E. (登録日: 2016-11-27, 公開日: 2017-11-01, 最終更新日: 2024-01-17)

• 主引用文献: Darby, J.F.,Atobe, M.,Firth, J.D.,Bond, P.,Davies, G.J.,O'Brien, P.,Hubbard, R.E.; Increase of enzyme activity through specific covalent modification with fragments.; Chem Sci, 8:7772-7779, 2017; PubMed: 29163914; DOI: 10.1039/c7sc01966a

実験手法

X-RAY DIFFRACTION (2.1 Å)