5M83

Translation initiation factor 4E in complex with (RP)-m2(7,2'O)GppSpA mRNA 5' cap analog

5M83 の概要

• エントリーDOI: 10.2210/pdb5m83/pdb
• 分子名称: Eukaryotic translation initiation factor 4E, [[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-sulfanyl-phosphoryl] [(2~{R},3~{R},4~{R},5~{R})-5-(2-azanyl-7-methyl-6-oxidanyl-purin-7-ium-9-yl)-4-methoxy-3-oxidanyl-oxolan-2-yl]methyl hydrogen phosphate, GLYCEROL, ... (4 entities in total)
• 機能のキーワード: protein-ligand complex, translation initiation factor, eif4e, m2(7, 2'o)gppspa, phosphorothioate, mrna 5' cap analog, translation, rna binding protein
• 由来する生物種: Mus musculus (House mouse)
• 細胞内の位置: Cytoplasm, P-body : P63073
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 46017.39

構造登録者

Warminski, M.,Nowak, E.,Kowalska, J.,Jemielity, J.,Nowotny, M. (登録日: 2016-10-28, 公開日: 2017-12-20, 最終更新日: 2024-01-17)

• 主引用文献: Warminski, M.,Nowak, E.,Kubacka, D.,Kowalska, J.,Nowotny, M.,Jemielity, J.; Translation initiation factor 4E in complex with (RP)-m2(7,2'O)GppSpA mRNA 5' cap analog; To Be Published,

実験手法

X-RAY DIFFRACTION (1.86 Å)