5M7W

Translation initiation factor 4E in complex with (SP)-m2(7,2'O)GppSpG mRNA 5' cap analog (beta-S-ARCA D2)

Summary for 5M7W

• Entry DOI: 10.2210/pdb5m7w/pdb
• Descriptor: Eukaryotic translation initiation factor 4E, [(2~{R},3~{R},4~{R},5~{R})-5-(2-azanyl-7-methyl-6-oxidanylidene-1~{H}-purin-7-ium-9-yl)-4-methoxy-3-oxidanyl-oxolan-2-yl]methyl [phosphonooxy(sulfanyl)phosphoryl] hydrogen phosphate, GLYCEROL, ... (4 entities in total)
• Functional Keywords: protein-ligand complex, translation initiation factor, eif4e, m2(7, 2'o)gppspg, beta-s-arca, phosphorothioate, mrna 5' cap analog, translation
• Biological source: Mus musculus (Mouse)
• Cellular location: Cytoplasm, P-body : P63073
• Total number of polymer chains: 4
• Total formula weight: 91037.87

Authors

Warminski, M.,Nowak, E.,Kowalska, J.,Jemielity, J.,Nowotny, M. (deposition date: 2016-10-28, release date: 2017-12-20, Last modification date: 2024-01-17)

• Primary citation: Warminski, M.,Nowak, E.,Kubacka, D.,Kowalska, J.,Nowotny, M.,Jemielity, J.; Translation initiation factor 4E in complex with (SP)-m2(7,2'O)GppSpG mRNA 5' cap analog (beta-S-ARCA D2); To Be Published,

Experimental method

X-RAY DIFFRACTION (1.97 Å)