5M6Z

The X-ray structure of human M189I PGK-1 mutant in partially closed conformation

5M6Z の概要

• エントリーDOI: 10.2210/pdb5m6z/pdb
• 分子名称: Phosphoglycerate kinase 1, 3-PHOSPHOGLYCERIC ACID, PHOSPHATE ION, ... (6 entities in total)
• 機能のキーワード: transferase, human phosphoglycerate kinase 1, m189i snp -derived mutant
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 45280.23

構造登録者

Ilari, A.,Fiorillo, A.,Petrosino, M.,Cipollone, A. (登録日: 2016-10-26, 公開日: 2017-11-29, 最終更新日: 2024-01-17)

• 主引用文献: Fiorillo, A.,Petrosino, M.,Ilari, A.,Pasquo, A.,Cipollone, A.,Maggi, M.,Chiaraluce, R.,Consalvi, V.; The phosphoglycerate kinase 1 variants found in carcinoma cells display different catalytic activity and conformational stability compared to the native enzyme.; PLoS ONE, 13:e0199191-e0199191, 2018; PubMed: 29995887; DOI: 10.1371/journal.pone.0199191

実験手法

X-RAY DIFFRACTION (1.67 Å)