Summary for 5M6R
| Descriptor | Porphobilinogen deaminase, 3-[4-(2-hydroxy-2-oxoethyl)-5-[[4-(2-hydroxy-2-oxoethyl)-5-[[4-(2-hydroxy-2-oxoethyl)-5-[[4-(2-hydroxy-2-oxoethyl)-3-(3-hydroxy-3-oxopropyl)-5-methyl-1~{H}-pyrrol-2-yl]methyl]-3-(3-hydroxy-3-oxopropyl)-1~{H}-pyrrol-2-yl]methyl]-3-(3-hydroxy-3-oxopropyl)-1~{H}-pyrrol-2-yl]methyl]-1~{H}-pyrrol-3-yl]propanoic acid, PHOSPHATE ION, ... (5 entities in total) |
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| Functional Keywords | porphobilinogen deaminase, heme biosynthesis, porphyria, hmbs, transferase |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 2 |
| Total molecular weight | 87638.27 |
| Authors | Pluta, P.,Millet, O.,Roversi, P.,Rojas, A.L.,Gu, S. (deposition date: 2016-10-25, release date: 2017-11-15, Last modification date: 2019-05-29) |
| Primary citation | Pluta, P.,Roversi, P.,Bernardo-Seisdedos, G.,Rojas, A.L.,Cooper, J.B.,Gu, S.,Pickersgill, R.W.,Millet, O. Structural basis of pyrrole polymerization in human porphobilinogen deaminase. Biochim Biophys Acta Gen Subj, 1862:1948-1955, 2018 PubMed: 29908816 (PDB entries with the same primary citation) DOI: 10.1016/j.bbagen.2018.06.013  Import into Mendeley |
| Experimental method | X-RAY DIFFRACTION (2.73 Å) |
