6TA8

Crystal structure of the epimerization domain from the third module of tyrocidine synthetase B, TycB3(E)

Replaces:  5M6P

Summary for 6TA8

• Entry DOI: 10.2210/pdb6ta8/pdb
• Descriptor: Tyrocidine synthase 2 (2 entities in total)
• Functional Keywords: nrps, epimerization domain, epimerisation domain, chloramphenicol acetyltransferase, epimerase, isomerase, biosynthetic protein
• Biological source: Brevibacillus parabrevis
• Total number of polymer chains: 2
• Total formula weight: 113721.05

Authors

Fage, C.D.,Marahiel, M.A. (deposition date: 2019-10-29, release date: 2020-11-18, Last modification date: 2024-01-24)

• Primary citation: Fage, C.D.,Kosol, S.,Jenner, M.,Oster, C.,Gallo, A.,Kaniusaite, M.,Steinbach, R.,Staniforth, M.,Stavros, V.G.,Marahiel, M.A.,Cryle, M.J.,Lewandowski, J.R.; Communication Breakdown: Dissecting the COM Interfaces between the Subunits of Nonribosomal Peptide Synthetases; Acs Catalysis, 2021; DOI: 10.1021/acscatal.1c02113

Experimental method

X-RAY DIFFRACTION (2.4 Å)