5M5O
Pseudo-atomic model of microtubule-bound S.pombe kinesin-5 motor domain in the AMPPNP state (based on cryo-electron microscopy experiment): the N-terminus adopts multiple conformations.
Summary for 5M5O
Entry DOI | 10.2210/pdb5m5o/pdb |
EMDB information | 3445 |
Descriptor | Tubulin alpha-1D chain, Tubulin beta-2B chain, Kinesin-like protein cut7, ... (8 entities in total) |
Functional Keywords | microtubule-bound s.pombe kinesin-5, motor domain, amppnp bound state, modeller 9.10 2013-08 complex, motor protein |
Biological source | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) More |
Cellular location | Cytoplasm, cytoskeleton : Q2HJ86 Q6B856 Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body: P24339 |
Total number of polymer chains | 3 |
Total formula weight | 143256.74 |
Authors | Goulet, A.,Moores, C.A.,Cross, R.A. (deposition date: 2016-10-22, release date: 2016-11-30, Last modification date: 2024-05-08) |
Primary citation | Britto, M.,Goulet, A.,Rizvi, S.,von Loeffelholz, O.,Moores, C.A.,Cross, R.A. Schizosaccharomyces pombe kinesin-5 switches direction using a steric blocking mechanism. Proc. Natl. Acad. Sci. U.S.A., 113:E7483-E7489, 2016 Cited by PubMed: 27834216DOI: 10.1073/pnas.1611581113 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (9.3 Å) |
Structure validation
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