5M4Q

Crystal Structure of Wild-Type Human Prolidase with Mn ions and Pro ligand

Summary for 5M4Q

• Entry DOI: 10.2210/pdb5m4q/pdb
• Related: 2OKN 5M4G 5M4J 5M4L
• Descriptor: Xaa-Pro dipeptidase, MANGANESE (II) ION, HYDROXIDE ION, ... (6 entities in total)
• Functional Keywords: prolidase, peptidase, hydrolysis, pita-bread, metalloenzyme, hydrolase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 108726.87

Authors

Wilk, P.,Weiss, M.S.,Mueller, U.,Dobbek, H. (deposition date: 2016-10-18, release date: 2017-07-12, Last modification date: 2020-04-22)

• Primary citation: Wilk, P.,Uehlein, M.,Kalms, J.,Dobbek, H.,Mueller, U.,Weiss, M.S.; Substrate specificity and reaction mechanism of human prolidase.; FEBS J., 284:2870-2885, 2017; PubMed: 28677335; DOI: 10.1111/febs.14158

Experimental method

X-RAY DIFFRACTION (1.73 Å)