5LY7
Crystal structure of NagZ H174A mutant from Pseudomonas aeruginosa in complex with the inhibitor 2-acetamido-1,2-dideoxynojirimycin
Summary for 5LY7
Entry DOI | 10.2210/pdb5ly7/pdb |
Descriptor | Beta-hexosaminidase, DI(HYDROXYETHYL)ETHER, 2-ACETAMIDO-1,2-DIDEOXYNOJIRMYCIN, ... (4 entities in total) |
Functional Keywords | cell-wall recycling beta-hexosaminidase pseudomonas aeruginosa inhibitor, gene regulation |
Biological source | Pseudomonas aeruginosa |
Cellular location | Cytoplasm : Q9HZK0 |
Total number of polymer chains | 2 |
Total formula weight | 77121.90 |
Authors | Acebron, I.,Artola-Recolons, C.,Mahasenan, K.,Mobashery, S.,Hermoso, J.A. (deposition date: 2016-09-25, release date: 2017-05-17, Last modification date: 2024-05-01) |
Primary citation | Acebron, I.,Mahasenan, K.V.,De Benedetti, S.,Lee, M.,Artola-Recolons, C.,Hesek, D.,Wang, H.,Hermoso, J.A.,Mobashery, S. Catalytic Cycle of the N-Acetylglucosaminidase NagZ from Pseudomonas aeruginosa. J. Am. Chem. Soc., 139:6795-6798, 2017 Cited by PubMed: 28482153DOI: 10.1021/jacs.7b01626 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.1 Å) |
Structure validation
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