5LXQ

Structure of PRL-1 in complex with the Bateman domain of CNNM2

Summary for 5LXQ

Entry DOI	10.2210/pdb5lxq/pdb
Descriptor	Protein tyrosine phosphatase type IVA 1, Metal transporter CNNM2, ADENOSINE-5'-TRIPHOSPHATE, ... (4 entities in total)
Functional Keywords	cyclin m, magnesium transport, acdp, metal transport
Biological source	Mus musculus (House Mouse) More
Total number of polymer chains	4
Total formula weight	82172.46
Authors	GIMENEZ-Mascarell, P.,Oyenarte, I.,Hardy, S.,Breiderhoff, T.,Stuiver, M.,Kostantin, E.,Diercks, T.,Pey, A.L.,Ereno-ORBEA, J.,Martinez-Chantar, M.L.,Khalaf-Nazzal, R.,Claverie-Martin, F.,Muller, D.,Tremblay, M.,Martinez-Cruz, L.A. (deposition date: 2016-09-22, release date: 2016-12-07, Last modification date: 2024-01-17)
Primary citation	Gimenez-Mascarell, P.,Oyenarte, I.,Hardy, S.,Breiderhoff, T.,Stuiver, M.,Kostantin, E.,Diercks, T.,Pey, A.L.,Ereno-Orbea, J.,Martinez-Chantar, M.L.,Khalaf-Nazzal, R.,Claverie-Martin, F.,Muller, D.,Tremblay, M.L.,Martinez-Cruz, L.A. Structural Basis of the Oncogenic Interaction of Phosphatase PRL-1 with the Magnesium Transporter CNNM2. J. Biol. Chem., 292:786-801, 2017 Cited by PubMed: 27899452 DOI: 10.1074/jbc.M116.759944 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.335 Å)

Structure validation