5LS3
Crystal structure of metallo-beta-lactamase SPM-1 with Y58C mutation
Summary for 5LS3
Entry DOI | 10.2210/pdb5ls3/pdb |
Descriptor | Beta-lactamase IMP-1, ZINC ION (3 entities in total) |
Functional Keywords | metallo-beta-lactamase, carbapenemase, hydrolase |
Biological source | Pseudomonas aeruginosa |
Total number of polymer chains | 2 |
Total formula weight | 56061.34 |
Authors | Hinchliffe, P.,Spencer, J. (deposition date: 2016-08-22, release date: 2017-03-15, Last modification date: 2024-01-17) |
Primary citation | Abboud, M.I.,Hinchliffe, P.,Brem, J.,Macsics, R.,Pfeffer, I.,Makena, A.,Umland, K.D.,Rydzik, A.M.,Li, G.B.,Spencer, J.,Claridge, T.D.,Schofield, C.J. (19) F-NMR Reveals the Role of Mobile Loops in Product and Inhibitor Binding by the Sao Paulo Metallo-beta-Lactamase. Angew. Chem. Int. Ed. Engl., 56:3862-3866, 2017 Cited by PubMed: 28252254DOI: 10.1002/anie.201612185 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.754 Å) |
Structure validation
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