5LRV
Structure of Cezanne/OTUD7B OTU domain bound to Lys11-linked diubiquitin
Summary for 5LRV
Entry DOI | 10.2210/pdb5lrv/pdb |
Descriptor | OTU domain-containing protein 7B, Polyubiquitin-B, PHOSPHATE ION, ... (6 entities in total) |
Functional Keywords | hydrolase, protease, deubiquitinase, otu domain |
Biological source | Homo sapiens (Human) More |
Cellular location | Cytoplasm : Q6GQQ9 Ubiquitin: Cytoplasm : P0CG47 P0CG47 |
Total number of polymer chains | 3 |
Total formula weight | 53976.38 |
Authors | Mevissen, T.E.T.,Kulathu, Y.,Mulder, M.P.C.,Geurink, P.P.,Maslen, S.L.,Gersch, M.,Elliott, P.R.,Burke, J.E.,van Tol, B.D.M.,Akutsu, M.,El Oualid, F.,Kawasaki, M.,Freund, S.M.V.,Ovaa, H.,Komander, D. (deposition date: 2016-08-22, release date: 2016-10-19, Last modification date: 2023-11-15) |
Primary citation | Mevissen, T.E.,Kulathu, Y.,Mulder, M.P.,Geurink, P.P.,Maslen, S.L.,Gersch, M.,Elliott, P.R.,Burke, J.E.,van Tol, B.D.,Akutsu, M.,El Oualid, F.,Kawasaki, M.,Freund, S.M.,Ovaa, H.,Komander, D. Molecular basis of Lys11-polyubiquitin specificity in the deubiquitinase Cezanne. Nature, 538:402-405, 2016 Cited by PubMed: 27732584DOI: 10.1038/nature19836 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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