5LPA
AadA E87Q in complex with ATP, calcium and dihydrostreptomycin
Summary for 5LPA
Entry DOI | 10.2210/pdb5lpa/pdb |
Descriptor | Streptomycin 3''-adenylyltransferase, ADENOSINE-5'-TRIPHOSPHATE, dihydrostreptomycin, ... (7 entities in total) |
Functional Keywords | transferase, aminoglycoside adenyl transferase, ant(3'')9, antibiotic resistance |
Biological source | Salmonella enterica subsp. enterica serovar Typhimurium |
Total number of polymer chains | 2 |
Total formula weight | 63829.28 |
Authors | Stern, A.L.,Van der Verren, S.E.,Selmer, M. (deposition date: 2016-08-12, release date: 2018-01-17, Last modification date: 2024-01-10) |
Primary citation | Stern, A.L.,Van der Verren, S.E.,Kanchugal P, S.,Nasvall, J.,Gutierrez-de-Teran, H.,Selmer, M. Structural mechanism of AadA, a dual-specificity aminoglycoside adenylyltransferase fromSalmonella enterica. J.Biol.Chem., 293:11481-11490, 2018 Cited by PubMed: 29871922DOI: 10.1074/jbc.RA118.003989 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.4 Å) |
Structure validation
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