5LNQ
Crystal structure of SCP2 thiolase from Leishmania mexicana. Complex of the C123A mutant with acetoacetyl-CoA.
Summary for 5LNQ
| Entry DOI | 10.2210/pdb5lnq/pdb |
| Descriptor | 3-ketoacyl-CoA thiolase-like protein, ACETOACETYL-COENZYME A (3 entities in total) |
| Functional Keywords | leishmania mexicana, scp2-thiolase, acetoacetyl-coa, lipid metabolism, transferase |
| Biological source | Leishmania mexicana |
| Total number of polymer chains | 4 |
| Total formula weight | 199458.52 |
| Authors | Harijan, R.K.,Kiema, T.-R.,Wierenga, R.K. (deposition date: 2016-08-06, release date: 2017-01-18, Last modification date: 2024-01-10) |
| Primary citation | Harijan, R.K.,Kiema, T.R.,Syed, S.M.,Qadir, I.,Mazet, M.,Bringaud, F.,Michels, P.A.M.,Wierenga, R.K. Crystallographic substrate binding studies of Leishmania mexicana SCP2-thiolase (type-2): unique features of oxyanion hole-1. Protein Eng. Des. Sel., 30:225-233, 2017 Cited by PubMed: 28062645DOI: 10.1093/protein/gzw080 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.98 Å) |
Structure validation
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