5LHU

ATP Phosphoribosyltransferase from Mycobacterium tuberculosis in complex with the allosteric inhibitor L-Histidine

5LHU の概要

• エントリーDOI: 10.2210/pdb5lhu/pdb
• 分子名称: ATP phosphoribosyltransferase, HISTIDINE, SULFATE ION, ... (5 entities in total)
• 機能のキーワード: atp-prtase, act, his g, histidine biosynthesis, transferase
• 由来する生物種: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 32510.66

構造登録者

de Chiara, C.,Pisco, J.P.,de Carvalho, L.P.,Smerdon, S.J.,Walker, P.A.,Ogrodowicz, R. (登録日: 2016-07-12, 公開日: 2017-06-21, 最終更新日: 2024-01-10)

• 主引用文献: Pisco, J.P.,Chiara, C.,Pacholarz, K.J.,Garza-Garcia, A.,Ogrodowicz, R.W.,Walker, P.A.,Barran, P.E.,Smerdon, S.J.,Carvalho, L.P.S.; Uncoupling conformational states from activity in an allosteric enzyme.; Nat Commun, 8:203-203, 2017; PubMed: 28781362; DOI: 10.1038/s41467-017-00224-0

実験手法

X-RAY DIFFRACTION (2.02 Å)