5LH9

Amine transaminase crystal structure from an uncultivated Pseudomonas species in the PLP-bound (internal aldimine) form

5LH9 の概要

• エントリーDOI: 10.2210/pdb5lh9/pdb
• 分子名称: OMEGA TRANSAMINASE, PYRIDOXAL-5'-PHOSPHATE (3 entities in total)
• 機能のキーワード: transaminase, aminotransferase, pyridoxal phosphate, plp-dependent enzyme fold type 1, transferase
• 由来する生物種: Pseudomonas sp.
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 199270.44

構造登録者

Reddem, E.,Thunnissen, A.M.W.H. (登録日: 2016-07-10, 公開日: 2017-03-22, 最終更新日: 2024-01-10)

• 主引用文献: Borner, T.,Ramisch, S.,Reddem, E.,Bartsch, S.,Vogel, A.,Thunnissen, A.M.W.H.,Adlercreutz, P.,Grey, C.; Explaining Operational Instability of Amine Transaminases: Substrate-Induced Inactivation Mechanism and Influence of Quaternary Structure on Enzyme-Cofactor Intermediate Stability.; Acs Catalysis, 7:1259-1269, 2017; DOI: 10.1021/acscatal.6b02100

実験手法

X-RAY DIFFRACTION (1.95 Å)