5LCW

Cryo-EM structure of the Anaphase-promoting complex/Cyclosome, in complex with the Mitotic checkpoint complex (APC/C-MCC) at 4.2 angstrom resolution

5LCW の概要

• エントリーDOI: 10.2210/pdb5lcw/pdb
• EMDBエントリー: 4037
• 分子名称: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 13, ... (18 entities in total)
• 機能のキーワード: complex, ubiquitin, e3 ligase, ubiquitin ligase, cullin, ring, cell cycle, mitosis, spindle checkpoint, degron
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 23
• 化学式量合計: 1331085.90

構造登録者

Alfieri, C.,Chang, L.,Zhang, Z.,Yang, J.,Maslen, S.,Skehel, M.,Barford, D. (登録日: 2016-06-22, 公開日: 2016-08-10, 最終更新日: 2019-10-23)

• 主引用文献: Alfieri, C.,Chang, L.,Zhang, Z.,Yang, J.,Maslen, S.,Skehel, M.,Barford, D.; Molecular basis of APC/C regulation by the spindle assembly checkpoint.; Nature, 536:431-436, 2016; PubMed: 27509861; DOI: 10.1038/nature19083

実験手法

ELECTRON MICROSCOPY (4 Å)