5L8W

Structure of USP12-UB-PRG/UAF1

Summary for 5L8W

• Entry DOI: 10.2210/pdb5l8w/pdb
• Descriptor: Ubiquitin carboxyl-terminal hydrolase 12, WD repeat-containing protein 48, Polyubiquitin-B, ... (7 entities in total)
• Functional Keywords: dub-activator complex usp1 paralog, structural protein
• Biological source: Homo sapiens (Human); More
• Cellular location: Nucleus : Q8TAF3; Ubiquitin: Cytoplasm : P0CG47
• Total number of polymer chains: 3
• Total formula weight: 117671.81

Authors

Dharadhar, S.,Sixma, T. (deposition date: 2016-06-08, release date: 2016-09-28, Last modification date: 2016-11-30)

• Primary citation: Dharadhar, S.,Clerici, M.,van Dijk, W.J.,Fish, A.,Sixma, T.K.; A conserved two-step binding for the UAF1 regulator to the USP12 deubiquitinating enzyme.; J.Struct.Biol., 196:437-447, 2016; PubMed: 27650958; DOI: 10.1016/j.jsb.2016.09.011

Experimental method

X-RAY DIFFRACTION (2.79 Å)