5L7G
MCR IN COMPLEX WITH ligand
Summary for 5L7G
Entry DOI | 10.2210/pdb5l7g/pdb |
Descriptor | Mineralocorticoid receptor, NCOA1 peptide, 1,2-ETHANEDIOL, ... (5 entities in total) |
Functional Keywords | mineralocorticoid receptor 2, signaling protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 36516.68 |
Authors | Edman, K.,Aagaard, A.,Backstrom, S.,Xue, Y. (deposition date: 2016-06-03, release date: 2016-12-07, Last modification date: 2024-05-08) |
Primary citation | Nordqvist, A.,O'Mahony, G.,Friden-Saxin, M.,Fredenwall, M.,Hogner, A.,Granberg, K.L.,Aagaard, A.,Backstrom, S.,Gunnarsson, A.,Kaminski, T.,Xue, Y.,Dellsen, A.,Hansson, E.,Hansson, P.,Ivarsson, I.,Karlsson, U.,Bamberg, K.,Hermansson, M.,Georgsson, J.,Lindmark, B.,Edman, K. Structure-Based Drug Design of Mineralocorticoid Receptor Antagonists to Explore Oxosteroid Receptor Selectivity. ChemMedChem, 12:50-65, 2017 Cited by PubMed: 27897427DOI: 10.1002/cmdc.201600529 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.01 Å) |
Structure validation
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