5L6Q
Refolded AL protein from cardiac amyloidosis
Summary for 5L6Q
Entry DOI | 10.2210/pdb5l6q/pdb |
Related | 4OD2 |
Descriptor | H5AL, ZINC ION, SODIUM ION, ... (8 entities in total) |
Functional Keywords | antibody, light chain, systemic al amyloidosis, amyloid fibrils, immune system |
Biological source | Homo sapiens |
Total number of polymer chains | 2 |
Total formula weight | 25213.06 |
Authors | Annamalai, K.,Liberta, F.,Vielberg, M.-T.,Lilie, H.,Guehrs, K.-H.,Schierhorn, A.,Koehler, R.,Schmidt, A.,Haupt, C.,Hegenbart, O.,Schoenland, S.,Groll, M.,Faendrich, M. (deposition date: 2016-05-31, release date: 2017-05-31, Last modification date: 2024-01-10) |
Primary citation | Annamalai, K.,Liberta, F.,Vielberg, M.T.,Close, W.,Lilie, H.,Guhrs, K.H.,Schierhorn, A.,Koehler, R.,Schmidt, A.,Haupt, C.,Hegenbart, U.,Schonland, S.,Schmidt, M.,Groll, M.,Fandrich, M. Common Fibril Structures Imply Systemically Conserved Protein Misfolding Pathways In Vivo. Angew. Chem. Int. Ed. Engl., 56:7510-7514, 2017 Cited by PubMed: 28544119DOI: 10.1002/anie.201701761 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.4 Å) |
Structure validation
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