5L0M

hLRH-1 DNA Binding Domain - 12bp Oct4 promoter complex

Summary for 5L0M

• Entry DOI: 10.2210/pdb5l0m/pdb
• Descriptor: Nuclear receptor subfamily 5 group A member 2, DNA (5'-D(*CP*TP*AP*GP*CP*CP*TP*TP*GP*AP*CP*C)-3'), DNA (5'-D(*GP*GP*TP*CP*AP*AP*GP*GP*CP*TP*AP*G)-3'), ... (6 entities in total)
• Functional Keywords: lrh-1, nuclear receptor, oct4, dbd, transcription-dna complex, transcription/dna
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 3
• Total formula weight: 20701.04

Authors

Tuntland, M.L.,Ortlund, E.A. (deposition date: 2016-07-27, release date: 2016-11-09, Last modification date: 2023-10-04)

• Primary citation: Weikum, E.R.,Tuntland, M.L.,Murphy, M.N.,Ortlund, E.A.; A Structural Investigation into Oct4 Regulation by Orphan Nuclear Receptors, Germ Cell Nuclear Factor (GCNF), and Liver Receptor Homolog-1 (LRH-1).; J. Mol. Biol., 428:4981-4992, 2016; PubMed: 27984042; DOI: 10.1016/j.jmb.2016.10.025

Experimental method

X-RAY DIFFRACTION (2.197 Å)