5KWQ

Two Tandem RRM Domains of FBP-Interacting Repressor (FIR), also Known as PUF60

Summary for 5KWQ

Entry DOI	10.2210/pdb5kwq/pdb
Descriptor	Poly(U)-binding-splicing factor PUF60 (1 entity in total)
Functional Keywords	tandem rrms, c-myc regulation, splicing factor, splicing
Biological source	Homo sapiens (Human)
Total number of polymer chains	2
Total formula weight	46817.07
Authors	Crichlow, G.V.,Yang, Y.,Zhou, H.,Lolis, E.J.,Braddock, D.T. (deposition date: 2016-07-18, release date: 2017-08-23, Last modification date: 2023-10-04)
Primary citation	Hsiao, H.T.,Crichlow, G.V.,Murphy, J.W.,Folta-Stogniew, E.J.,Lolis, E.J.,Braddock, D.T. Unraveling the mechanism of recognition of the 3' splice site of the adenovirus major late promoter intron by the alternative splicing factor PUF60. Plos One, 15:e0242725-e0242725, 2020 Cited by PubMed: 33253191 DOI: 10.1371/journal.pone.0242725 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation