5KTR

Crystal structure of Pyrococcus horikoshii quinolinate synthase (NadA) with bound maleate and Fe4S4 cluster

Summary for 5KTR

Entry DOI	10.2210/pdb5ktr/pdb
Related	5KTM 5KTN 5KTO 5KTP 5KTS 5KTT
Descriptor	Quinolinate synthase A, IRON/SULFUR CLUSTER, MALEIC ACID, ... (6 entities in total)
Functional Keywords	dehydratase, iron-sulfur cluster, substrate analog complex, biosynthetic enzyme, transferase
Biological source	Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
Total number of polymer chains	1
Total formula weight	35174.54
Authors	Fenwick, M.K.,Ealick, S.E. (deposition date: 2016-07-12, release date: 2016-07-27, Last modification date: 2023-10-04)
Primary citation	Fenwick, M.K.,Ealick, S.E. Crystal Structures of the Iron-Sulfur Cluster-Dependent Quinolinate Synthase in Complex with Dihydroxyacetone Phosphate, Iminoaspartate Analogues, and Quinolinate. Biochemistry, 55:4135-4139, 2016 Cited by PubMed: 27404889 DOI: 10.1021/acs.biochem.6b00626 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.34 Å)

Structure validation