5KTO

Crystal structure of Pyrococcus horikoshii quinolinate synthase (NadA) with bound quinolinate and Fe4S4 cluster

Summary for 5KTO

• Entry DOI: 10.2210/pdb5kto/pdb
• Related: 5KTM 5KTN 5KTP 5KTR 5KTS 5KTT
• Descriptor: Quinolinate synthase A, IRON/SULFUR CLUSTER, QUINOLINIC ACID, ... (6 entities in total)
• Functional Keywords: dehydratase, iron-sulfur cluster, product complex, biosynthetic enzyme, transferase
• Biological source: Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
• Total number of polymer chains: 1
• Total formula weight: 35445.86

Authors

Fenwick, M.K.,Ealick, S.E. (deposition date: 2016-07-12, release date: 2016-07-27, Last modification date: 2023-10-04)

• Primary citation: Fenwick, M.K.,Ealick, S.E.; Crystal Structures of the Iron-Sulfur Cluster-Dependent Quinolinate Synthase in Complex with Dihydroxyacetone Phosphate, Iminoaspartate Analogues, and Quinolinate.; Biochemistry, 55:4135-4139, 2016; PubMed: 27404889; DOI: 10.1021/acs.biochem.6b00626

Experimental method

X-RAY DIFFRACTION (1.442 Å)