5KSJ
Crystal structure of deoxygenated hemoglobin in complex with Sphingosine phosphate
Summary for 5KSJ
Entry DOI | 10.2210/pdb5ksj/pdb |
Related | 5KSI |
Descriptor | Hemoglobin subunit alpha, Hemoglobin subunit beta, PROTOPORPHYRIN IX CONTAINING FE, ... (5 entities in total) |
Functional Keywords | hemoglobin, sphingosine-1-phosphate, complex, allosteric effector, oxygen transport |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 65305.99 |
Authors | Ahmed, M.H.,Safo, M.K.,Xia, Y. (deposition date: 2016-07-08, release date: 2017-07-26, Last modification date: 2023-10-04) |
Primary citation | Sun, K.,D'Alessandro, A.,Ahmed, M.H.,Zhang, Y.,Song, A.,Ko, T.P.,Nemkov, T.,Reisz, J.A.,Wu, H.,Adebiyi, M.,Peng, Z.,Gong, J.,Liu, H.,Huang, A.,Wen, Y.E.,Wen, A.Q.,Berka, V.,Bogdanov, M.V.,Abdulmalik, O.,Han, L.,Tsai, A.L.,Idowu, M.,Juneja, H.S.,Kellems, R.E.,Dowhan, W.,Hansen, K.C.,Safo, M.K.,Xia, Y. Structural and Functional Insight of Sphingosine 1-Phosphate-Mediated Pathogenic Metabolic Reprogramming in Sickle Cell Disease. Sci Rep, 7:15281-15281, 2017 Cited by PubMed: 29127281DOI: 10.1038/s41598-017-13667-8 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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