5KL5
Wilms Tumor Protein (WT1) ZnF2-4 Q369H in complex with carboxylated DNA
Summary for 5KL5
Entry DOI | 10.2210/pdb5kl5/pdb |
Related | 5KL2 5KL3 5KL4 5KL6 5KL7 |
Descriptor | Wilms tumor protein, DNA (5'-D(*AP*GP*CP*GP*TP*GP*GP*GP*(1CC)P*GP*T)-3'), DNA (5'-D(*TP*AP*(5CM)P*GP*CP*CP*CP*AP*CP*GP*C)-3'), ... (6 entities in total) |
Functional Keywords | wilms tumor protein, wt1, zinc finger, 5-carboxyl cytosine, transcription-dna complex, transcription/dna |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 18318.62 |
Authors | Hashimoto, H.,Cheng, X. (deposition date: 2016-06-23, release date: 2016-09-14, Last modification date: 2023-09-27) |
Primary citation | Hashimoto, H.,Zhang, X.,Zheng, Y.,Wilson, G.G.,Cheng, X. Denys-Drash syndrome associated WT1 glutamine 369 mutants have altered sequence-preferences and altered responses to epigenetic modifications. Nucleic Acids Res., 44:10165-10176, 2016 Cited by PubMed: 27596598DOI: 10.1093/nar/gkw766 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.289 Å) |
Structure validation
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