5KKA

E. coli malate dehydrogenase with the inhibitor 6DHNAD

Summary for 5KKA

• Entry DOI: 10.2210/pdb5kka/pdb
• Related: 5KKC
• Descriptor: Malate dehydrogenase, [[(2~{R},3~{S},4~{R},5~{R})-5-(5-aminocarbonyl-2~{H}-pyridin-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl hydrogen phosphate (3 entities in total)
• Functional Keywords: malate, dehydrogenase, 6dhnad, inhibitor, beta- 6-dihydronicotimide adenine dinucleotide, oxidoreductase
• Biological source: Escherichia coli (strain K12)
• Total number of polymer chains: 2
• Total formula weight: 66067.23

Authors

Meneely, K.M.,Lamb, A.L.,Moran, G.R. (deposition date: 2016-06-21, release date: 2016-11-02, Last modification date: 2023-09-27)

• Primary citation: Beaupre, B.A.,Roman, J.V.,Hoag, M.R.,Meneely, K.M.,Silvaggi, N.R.,Lamb, A.L.,Moran, G.R.; Ligand binding phenomena that pertain to the metabolic function of renalase.; Arch.Biochem.Biophys., 612:46-56, 2016; PubMed: 27769837; DOI: 10.1016/j.abb.2016.10.011

Experimental method

X-RAY DIFFRACTION (1.75 Å)