5KIL
CmlA beta-hydroxylase E377D mutant
Summary for 5KIL
| Entry DOI | 10.2210/pdb5kil/pdb |
| Related | 4JO0 5kik |
| Descriptor | CmlA protein, MU-OXO-DIIRON, POTASSIUM ION, ... (5 entities in total) |
| Functional Keywords | oxygen activation, diiron cluster, antibiotic biosynthesis, beta-hydroxylase, oxidoreductase |
| Biological source | Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745) |
| Total number of polymer chains | 1 |
| Total formula weight | 62488.71 |
| Authors | Knoot, C.J.,Lipscomb, J.D. (deposition date: 2016-06-16, release date: 2017-04-26, Last modification date: 2023-09-27) |
| Primary citation | Jasniewski, A.J.,Knoot, C.J.,Lipscomb, J.D.,Que, L. A Carboxylate Shift Regulates Dioxygen Activation by the Diiron Nonheme beta-Hydroxylase CmlA upon Binding of a Substrate-Loaded Nonribosomal Peptide Synthetase. Biochemistry, 55:5818-5831, 2016 Cited by PubMed: 27668828DOI: 10.1021/acs.biochem.6b00834 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.72 Å) |
Structure validation
Download full validation report
