5KHT

Crystal structure of the N-terminal fragment of tropomyosin isoform Tpm1.1 at 1.5 A resolution

Summary for 5KHT

Entry DOI	10.2210/pdb5kht/pdb
Descriptor	Tropomyosin alpha-1 chain,General control protein GCN4, DI(HYDROXYETHYL)ETHER (3 entities in total)
Functional Keywords	tropomyosin, coiled coil, actin-binding protein
Biological source	Homo sapiens (Human) More
Total number of polymer chains	4
Total formula weight	22237.67
Authors	Kostyukova, A.S.,Krieger, I.,Yoon, Y.-H.,Tolkatchev, D.,Samatey, F.A. (deposition date: 2016-06-15, release date: 2017-06-21, Last modification date: 2024-04-03)
Primary citation	Ly, T.,Krieger, I.,Tolkatchev, D.,Krone, C.,Moural, T.,Samatey, F.A.,Kang, C.,Kostyukova, A.S. Structural destabilization of tropomyosin induced by the cardiomyopathy-linked mutation R21H. Protein Sci., 27:498-508, 2018 Cited by PubMed: 29105867 DOI: 10.1002/pro.3341 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.4964 Å)

Structure validation