5KHT

Crystal structure of the N-terminal fragment of tropomyosin isoform Tpm1.1 at 1.5 A resolution

5KHT の概要

• エントリーDOI: 10.2210/pdb5kht/pdb
• 分子名称: Tropomyosin alpha-1 chain,General control protein GCN4, DI(HYDROXYETHYL)ETHER (3 entities in total)
• 機能のキーワード: tropomyosin, coiled coil, actin-binding protein
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 22237.67

構造登録者

Kostyukova, A.S.,Krieger, I.,Yoon, Y.-H.,Tolkatchev, D.,Samatey, F.A. (登録日: 2016-06-15, 公開日: 2017-06-21, 最終更新日: 2024-04-03)

• 主引用文献: Ly, T.,Krieger, I.,Tolkatchev, D.,Krone, C.,Moural, T.,Samatey, F.A.,Kang, C.,Kostyukova, A.S.; Structural destabilization of tropomyosin induced by the cardiomyopathy-linked mutation R21H.; Protein Sci., 27:498-508, 2018; PubMed: 29105867; DOI: 10.1002/pro.3341

実験手法

X-RAY DIFFRACTION (1.4964 Å)