5KHP

Tightening the Recognition of Tetravalent Zr and Th Complexes by the Siderophore-Binding Mammalian Protein Siderocalin for Theranostic Applications

5KHP の概要

• エントリーDOI: 10.2210/pdb5khp/pdb
• 関連するPDBエントリー: 5KID
• 分子名称: Neutrophil gelatinase-associated lipocalin, ZIRCONIUM ION, N,N'-(butane-1,4-diyl)bis(N-{3-[(2,3-dihydroxybenzene-1-carbonyl)amino]propyl}-2,3-dihydroxybenzamide), ... (6 entities in total)
• 機能のキーワード: siderophore-binding, ngal, metal binding protein
• 由来する生物種: Homo sapiens (Human)
• 細胞内の位置: Secreted : P80188
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 65476.24

構造登録者

Rupert, P.B.,Strong, R.K. (登録日: 2016-06-15, 公開日: 2017-04-26, 最終更新日: 2023-09-27)

• 主引用文献: Captain, I.,Deblonde, G.J.,Rupert, P.B.,An, D.D.,Illy, M.C.,Rostan, E.,Ralston, C.Y.,Strong, R.K.,Abergel, R.J.; Engineered Recognition of Tetravalent Zirconium and Thorium by Chelator-Protein Systems: Toward Flexible Radiotherapy and Imaging Platforms.; Inorg Chem, 55:11930-11936, 2016; PubMed: 27802058; DOI: 10.1021/acs.inorgchem.6b02041

実験手法

X-RAY DIFFRACTION (2.65 Å)