5KCP
horse liver S48T alcohol dehydrogenase complexed with NAD and pentafluorobenzyl alcohol
Summary for 5KCP
Entry DOI | 10.2210/pdb5kcp/pdb |
Related | 4DWV 5KCZ 5KJ1 5KJ6 5KJC 5KJE 5KJF |
Descriptor | Alcohol dehydrogenase E chain, ZINC ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE (ACIDIC FORM), ... (6 entities in total) |
Functional Keywords | ser48 to thr-48 substitution, horse liver alcohol dehydrogenase, nad-pentafluorobenzyl alcohol, oxidoreductase |
Biological source | Equus caballus (Horse) |
Total number of polymer chains | 2 |
Total formula weight | 82588.14 |
Authors | Plapp, B.V. (deposition date: 2016-06-06, release date: 2016-06-29, Last modification date: 2023-09-27) |
Primary citation | Kim, K.,Plapp, B.V. Inversion of substrate stereoselectivity of horse liver alcohol dehydrogenase by substitutions of Ser-48 and Phe-93. Chem. Biol. Interact., 276:77-87, 2017 Cited by PubMed: 28025168DOI: 10.1016/j.cbi.2016.12.016 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.1 Å) |
Structure validation
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