horse liver S48T alcohol dehydrogenase complexed with NAD and pentafluorobenzyl alcohol

Summary for 5KCP

Related4DWV 5KCZ 5KJ1 5KJ6 5KJC 5KJE 5KJF
DescriptorAlcohol dehydrogenase E chain, ZINC ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE (ACIDIC FORM), ... (6 entities in total)
Functional Keywordsser48 to thr-48 substitution, horse liver alcohol dehydrogenase, nad-pentafluorobenzyl alcohol, oxidoreductase
Biological sourceEquus caballus (Horse)
Cellular locationCytoplasm P00327
Total number of polymer chains2
Total molecular weight82588.14
Plapp, B.V. (deposition date: 2016-06-06, release date: 2016-06-29, Last modification date: 2017-11-22)
Primary citation
Kim, K.,Plapp, B.V.
Inversion of substrate stereoselectivity of horse liver alcohol dehydrogenase by substitutions of Ser-48 and Phe-93.
Chem. Biol. Interact., 276:77-87, 2017
PubMed: 28025168 (PDB entries with the same primary citation)
DOI: 10.1016/j.cbi.2016.12.016
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.138100.2%0.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution