5K8U

Crystal structure of ZIKV NS3 helicase in complex with ADP and Mn2+

Summary for 5K8U

• Entry DOI: 10.2210/pdb5k8u/pdb
• Related: 5JWH 5K8I 5K8L 5K8T
• Descriptor: zika virus NS3 helicase, ADENOSINE-5'-DIPHOSPHATE, MANGANESE (II) ION, ... (6 entities in total)
• Functional Keywords: ntpase, helicase, hydrolase
• Biological source: Zika virus
• Total number of polymer chains: 1
• Total formula weight: 52066.13

Authors

Cao, X.,Li, Y.,Jin, T. (deposition date: 2016-05-31, release date: 2016-11-09, Last modification date: 2024-03-20)

• Primary citation: Cao, X.,Li, Y.,Jin, X.,Li, Y.,Guo, F.,Jin, T.; Molecular mechanism of divalent-metal-induced activation of NS3 helicase and insights into Zika virus inhibitor design.; Nucleic Acids Res., 44:10505-10514, 2016; PubMed: 27915293; DOI: 10.1093/nar/gkw941

Experimental method

X-RAY DIFFRACTION (1.601 Å)