5K2C

1.9 angstrom A2a adenosine receptor structure with sulfur SAD phasing and phase extension using XFEL data

5K2C の概要

• エントリーDOI: 10.2210/pdb5k2c/pdb
• 関連するPDBエントリー: 5K2A 5K2B 5K2D
• 分子名称: Adenosine receptor A2a/Soluble cytochrome b562 chimera, 4-{2-[(7-amino-2-furan-2-yl[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino]ethyl}phenol, SODIUM ION, ... (8 entities in total)
• 機能のキーワード: a2a adenosine receptor, sulfur sad, gpcr, membrane protein, structural genomics, psi-biology, gpcr network
• 由来する生物種: Homo sapiens, Escherichia coli (Human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 58273.16

構造登録者

Batyuk, A.,Galli, L.,Ishchenko, A.,Han, G.W.,Gati, C.,Popov, P.,Lee, M.-Y.,Stauch, B.,White, T.A.,Barty, A.,Aquila, A.,Hunter, M.S.,Liang, M.,Boutet, S.,Pu, M.,Liu, Z.-J.,Nelson, G.,James, D.,Li, C.,Zhao, Y.,Spence, J.C.H.,Liu, W.,Fromme, P.,Katritch, V.,Weierstall, U.,Stevens, R.C.,Cherezov, V.,GPCR Network (GPCR) (登録日: 2016-05-18, 公開日: 2016-09-21, 最終更新日: 2018-11-28)

• 主引用文献: Batyuk, A.,Galli, L.,Ishchenko, A.,Han, G.W.,Gati, C.,Popov, P.A.,Lee, M.Y.,Stauch, B.,White, T.A.,Barty, A.,Aquila, A.,Hunter, M.S.,Liang, M.,Boutet, S.,Pu, M.,Liu, Z.J.,Nelson, G.,James, D.,Li, C.,Zhao, Y.,Spence, J.C.,Liu, W.,Fromme, P.,Katritch, V.,Weierstall, U.,Stevens, R.C.,Cherezov, V.; Native phasing of x-ray free-electron laser data for a G protein-coupled receptor.; Sci Adv, 2:e1600292-e1600292, 2016; PubMed: 27679816; DOI: 10.1126/sciadv.1600292

実験手法

X-RAY DIFFRACTION (1.9 Å)